Tramadol (trans- (±) -2 – [(Dimethylamino) methyl] -1- (3-methoxyphenyl) cyclohexanol (as hydrochloride) is an opioid synthetic analgesic, belongs to the group of partial opioid receptor agonists. It activates opioid receptors (mu, delta, kappa) on the pre- and postsynaptic membranes of the afferent fibers of the nociceptive system in the brain and gastrointestinal tract.It has a strong analgesic activity, gives a quick and long-lasting effect. Analgesic effect develops 15-30 minutes after ingestion and lasts up to 6 hours Chemical formulas C16H25NO2.

Tramadol is available in the form of ampoules for injection, tablets and capsules. The drug is a white crystalline powder, odorless, bitter taste, well soluble in water and ethanol.

Tramadol is 10 times weaker than codeine, and 6000 times weaker than morphine at the same dosage, while the severity of analgesic action is only 5-10 times weaker than morphine.

As a rule, this substance is used in medicine – one cannot do without it in case of unbearable physical pain. However, Tramadol has long ceased to be just a drug. More and more often it is used as a narcotic drug. Tramadol, as a narcotic substance, is among the most powerful and dangerous drugs.

Since Tramadol is an opiate (opiate) drug, it, like other opiates (heroin), is addictive. When you stop taking Tramadol there is severe withdrawal, withdrawal. The addiction to the drug develops extremely quickly, so it is constantly necessary to increase the dose. Because of the availability of adolescents, Tramadol sits down and is often the first drug of a dependent person. Often it is used because of the inability to get heroin. Often they are trying to make a break.

The first reception leads to euphoria, which gives way to nightmares and the fear of loneliness. Further hallucinations are added to the euphoria, and then the appetite disappears, sometimes completely, but I really want to drink. Then the addict becomes less active, sometimes crying and often irritable. Under the drug, euphoria is replaced by a simply cheerful mood, but the effect quickly passes. It is also observed: sweating, increased urination, dizziness, headache, weakness, fatigue, lethargy, paradoxical stimulation of the central nervous system (nervousness, agitation, anxiety, tremors, muscle spasms, euphoria, emotional lability, hallucinations), drowsiness, sleep disturbances, confusion of consciousness, impaired coordination of movements, convulsions of central genesis (with intravenous administration in high doses or with simultaneous prescription of antipsychotic drugs (neuroleptics), depression, amnesia, cognitive impairment, paresthesia, gait imbalance, dry mouth, nausea, vomiting, flatulence, abdominal pain, constipation or diarrhea, difficulty swallowing. Overdosemiosis, vomiting, collapse, coma, cramps, respiratory depression center, apnea.

The use of Tramadol causes mental and physical dependence. Overdosing is deadly. Prolonged use of this drug damages the internal organs, especially the liver. Adolescents using Tramadol may have problems with sexual function in the future (its breakdown products accumulate in the testicles in men). The use of Tramadol greatly affects the intellect and the emotional sphere: even after the cessation of its use, inhibition persists for a long time. Tramadol can cause seizures that are similar to epileptic seizures, which are manifested by loss of consciousness, convulsions, and discharge of foam from the mouth. During such an attack, it is very important to quickly unclench the victim (you can use a spoon) and fix the tongue. If this is not done, death by suffocation may occur.